{"id":14857,"date":"2026-01-23T08:00:08","date_gmt":"2026-01-23T05:00:08","guid":{"rendered":"https:\/\/mdplusbio.com\/natural-dht-blockers-how-saw-palmetto-fights-hair-loss\/"},"modified":"2026-01-23T17:57:42","modified_gmt":"2026-01-23T14:57:42","slug":"dogal-dht-engelleyiciler-saw-palmetto","status":"publish","type":"post","link":"https:\/\/mdplusbio.com\/tr\/dogal-dht-engelleyiciler-saw-palmetto\/","title":{"rendered":"Do\u011fal DHT Engelleyiciler: Saw Palmetto Sa\u00e7 D\u00f6k\u00fclmesiyle Nas\u0131l M\u00fccadele Eder?"},"content":{"rendered":"\t\t
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Sa\u00e7 d\u00f6k\u00fclmesi, d\u00fcnya genelinde en yayg\u0131n estetik sorunlardan biridir. Hem erkeklerde hem de kad\u0131nlarda, sorunun merkezinde \u00e7o\u011fu zaman tek bir hormon yer al\u0131r: DHT (dihidrotestosteron)<\/strong>. Zamanla DHT, sa\u00e7 k\u00f6klerini zay\u0131flat\u0131r, sa\u00e7\u0131n b\u00fcy\u00fcme d\u00f6ng\u00fcs\u00fcn\u00fc k\u0131salt\u0131r ve giderek incelme ile sa\u00e7 kayb\u0131na yol a\u00e7ar.<\/p>

Finasterid ve minoksidil gibi farmakolojik tedaviler h\u00e2l\u00e2 yayg\u0131n olarak kullan\u0131lmaktad\u0131r. Ancak g\u00fcn\u00fcm\u00fczde giderek daha fazla ki\u015fi, daha az yan etki riskiyle sa\u00e7 sa\u011fl\u0131\u011f\u0131n\u0131 destekleyen do\u011fal DHT engelleyicilere<\/strong> y\u00f6nelmektedir. Bu noktada Saw Palmetto<\/strong>, en \u00e7ok ara\u015ft\u0131r\u0131lan ve en yayg\u0131n kullan\u0131lan do\u011fal se\u00e7enek olarak \u00f6ne \u00e7\u0131kar.<\/p>

S\u0131kl\u0131kla \u201cdo\u011fal finasterid\u201d<\/em> olarak an\u0131lan Saw Palmetto, DHT aktivitesini azaltma, sa\u00e7 k\u00f6klerini koruma ve daha sa\u011fl\u0131kl\u0131 sa\u00e7 b\u00fcy\u00fcmesini destekleme potansiyeli nedeniyle bilimsel ilgi g\u00f6rmektedir. Bu yaz\u0131da Saw Palmetto\u2019nun nas\u0131l \u00e7al\u0131\u015ft\u0131\u011f\u0131n\u0131, bilimsel verilerin ne s\u00f6yledi\u011fini ve uzun vadeli bir sa\u00e7 bak\u0131m stratejisinde nas\u0131l etkili \u015fekilde kullan\u0131labilece\u011fini ele al\u0131yoruz.<\/p>

\"Scientific-Studies-on-Saw-Palmetto-\"<\/p>

DHT ve Sa\u00e7 D\u00f6k\u00fclmesini Anlamak<\/h2>

DHT, testosteronun 5-alfa red\u00fcktaz<\/strong> enzimi arac\u0131l\u0131\u011f\u0131yla d\u00f6n\u00fc\u015fmesi sonucu olu\u015fan bir hormondur. V\u00fccutta normal i\u015flevleri olsa da, genetik olarak hassas sa\u00e7 k\u00f6kleri \u00fczerinde olumsuz etkilere yol a\u00e7abilir.<\/p>

Zamanla sa\u00e7 derisinde y\u00fcksek DHT seviyeleri \u015funlara neden olabilir:<\/strong><\/p>

  • Sa\u00e7 k\u00f6klerinin k\u00fc\u00e7\u00fclmesi (miniaturizasyon)<\/li>
  • Anajen (b\u00fcy\u00fcme) faz\u0131n\u0131n k\u0131salmas\u0131<\/li>
  • Daha ince ve zay\u0131f sa\u00e7 telleri<\/li>
  • Son a\u015famada sa\u00e7 \u00fcretiminin tamamen durmas\u0131<\/li><\/ul>

    Bu s\u00fcre\u00e7 androjenetik alopesi<\/strong> (erkek veya kad\u0131n tipi sa\u00e7 d\u00f6k\u00fclmesi) olarak adland\u0131r\u0131l\u0131r.<\/p>

    Kimler Daha Fazla Etkilenir?<\/h2>
    • Erkekler:<\/strong> Al\u0131n \u00e7izgisinde gerileme ve tepe b\u00f6lgesinde seyrelme<\/li>
    • Kad\u0131nlar:<\/strong> Sa\u00e7 ayr\u0131m \u00e7izgisinde yayg\u0131n incelme veya genel yo\u011funluk kayb\u0131<\/li><\/ul>

      DHT\u2019yi Engellemek Neden \u00d6nemlidir?<\/h2>

      DHT aktivitesi kontrol alt\u0131na al\u0131nmazsa, sa\u00e7 k\u00f6k\u00fc k\u00fc\u00e7\u00fclmesi ilerleyici \u015fekilde devam eder. DHT\u2019yi azaltmak \u2014 ister ila\u00e7larla ister do\u011fal engelleyicilerle \u2014 bu s\u00fcreci yava\u015flatabilir, mevcut sa\u00e7lar\u0131 koruyabilir ve baz\u0131 durumlarda yeniden sa\u00e7 \u00e7\u0131k\u0131\u015f\u0131n\u0131 destekleyebilir.<\/p>

      Saw Palmetto: Do\u011fal Bir DHT Engelleyici<\/h2>

      Saw Palmetto (Serenoa repens)<\/strong>, Kuzey Amerika\u2019ya \u00f6zg\u00fc k\u00fc\u00e7\u00fck bir palmiye t\u00fcr\u00fcd\u00fcr. Meyveleri y\u00fczy\u0131llard\u0131r geleneksel t\u0131pta kullan\u0131lmakta ve g\u00fcn\u00fcm\u00fczde hormonal denge ile sa\u00e7 sa\u011fl\u0131\u011f\u0131 \u00fczerindeki etkileri a\u00e7\u0131s\u0131ndan kapsaml\u0131 \u015fekilde ara\u015ft\u0131r\u0131lmaktad\u0131r.<\/p>

      Saw Palmetto Nas\u0131l Etki Eder?<\/h2>

      Ara\u015ft\u0131rmalar, Saw Palmetto\u2019nun sa\u00e7 sa\u011fl\u0131\u011f\u0131n\u0131 birka\u00e7 mekanizma \u00fczerinden destekledi\u011fini g\u00f6stermektedir:<\/p>

      • 5-alfa red\u00fcktaz enzimini bask\u0131layarak testosteronun DHT\u2019ye d\u00f6n\u00fc\u015f\u00fcm\u00fcn\u00fc azalt\u0131r<\/li>
      • DHT\u2019nin sa\u00e7 k\u00f6klerine ba\u011flanmas\u0131n\u0131 s\u0131n\u0131rlar<\/li>
      • Sa\u00e7 k\u00f6k\u00fc b\u00fct\u00fcnl\u00fc\u011f\u00fcn\u00fc destekler ve miniaturizasyonu \u00f6nlemeye yard\u0131mc\u0131 olur<\/li>
      • Anti-inflamatuar ya\u011f asitleri ve fitosteroller sayesinde sa\u00e7 derisi ortam\u0131n\u0131 iyile\u015ftirir<\/li><\/ul>

        Neden \u201cDo\u011fal Finasterid\u201d Olarak Adland\u0131r\u0131l\u0131r?<\/h2>

        Finasterid, 5-alfa red\u00fcktaz enzimini farmakolojik d\u00fczeyde engeller. Saw Palmetto ise ayn\u0131 biyolojik yolu bitkisel biyoaktif bile\u015fenler arac\u0131l\u0131\u011f\u0131yla hedef al\u0131r. Etkisi daha hafiftir; bu nedenle daha do\u011fal bir yakla\u015f\u0131m arayanlar veya sistemik yan etkilerden \u00e7ekinenler taraf\u0131ndan tercih edilir.<\/p>

        Saw Palmetto Hakk\u0131nda Bilimsel Kan\u0131tlar<\/h2>

        Saw Palmetto, sa\u00e7 d\u00f6k\u00fclmesi y\u00f6netiminde klinik verilerle desteklenen az say\u0131daki bitkisel i\u00e7erikten biridir.<\/p>

        \u00d6ne \u00c7\u0131kan Ara\u015ft\u0131rmalar<\/strong><\/p>

        • 2002 \u2013 Journal of Alternative and Complementary Medicine<\/strong>
          Androjenetik alopesisi olan erkeklerin yakla\u015f\u0131k %60\u2019\u0131nda Saw Palmetto kullan\u0131m\u0131 sonras\u0131 iyile\u015fme g\u00f6zlemlenmi\u015ftir.<\/li>
        • 2012 \u2013 International Journal of Immunopathology and Pharmacology<\/strong>
          Saw Palmetto i\u00e7eren topikal \u00fcr\u00fcnler, hafif\u2013orta dereceli sa\u00e7 d\u00f6k\u00fclmesinde sa\u00e7 yo\u011funlu\u011funu art\u0131rm\u0131\u015f ve d\u00f6k\u00fclmeyi azaltm\u0131\u015ft\u0131r.<\/li>
        • 2014 \u2013 Randomize Kontroll\u00fc \u00c7al\u0131\u015fma<\/strong>
          Finasterid ile kar\u015f\u0131la\u015ft\u0131r\u0131ld\u0131\u011f\u0131nda Saw Palmetto daha hafif ancak anlaml\u0131 sonu\u00e7lar g\u00f6stermi\u015f, daha az yan etki bildirilmi\u015ftir.<\/li><\/ul>

          Ara\u015ft\u0131rmalar\u0131n S\u0131n\u0131rlamalar\u0131<\/strong><\/p>

          • \u0130la\u00e7 \u00e7al\u0131\u015fmalar\u0131na k\u0131yasla daha k\u00fc\u00e7\u00fck \u00f6rneklem gruplar\u0131<\/li>
          • Doz ve form\u00fclasyon farkl\u0131l\u0131klar\u0131<\/li>
          • Daha fazla standartla\u015ft\u0131r\u0131lm\u0131\u015f \u00e7al\u0131\u015fmaya ihtiya\u00e7 duyulmas\u0131<\/li><\/ul>

            Sonu\u00e7:<\/strong> Saw Palmetto bir mucize tedavi de\u011fildir; ancak DHT\u2019ye ba\u011fl\u0131 sa\u00e7 d\u00f6k\u00fclmesini azaltmada bilimsel olarak en g\u00fc\u00e7l\u00fc desteklenen do\u011fal se\u00e7eneklerden biridir.<\/p>

            Saw Palmetto Nas\u0131l Etkili Kullan\u0131l\u0131r?<\/h2>

            Etkili sonu\u00e7lar i\u00e7in d\u00fczenli kullan\u0131m<\/strong> ve do\u011fru form\u00fclasyon<\/strong> b\u00fcy\u00fck \u00f6nem ta\u015f\u0131r.<\/p>

            Oral (A\u011f\u0131zdan) Takviyeler<\/strong><\/p>

            • Genellikle %85\u201395 ya\u011f asitleri ve steroller i\u00e7erecek \u015fekilde standardize edilir<\/li>
            • Yayg\u0131n doz: g\u00fcnde 160\u2013320 mg<\/strong><\/li>
            • Sistemik DHT d\u00fczenlemesi i\u00e7in uygundur<\/li><\/ul>

              S\u0131kl\u0131kla biotin, \u00e7inko, keratin ve adaptogen bitkilerle birlikte kullan\u0131larak sa\u00e7 g\u00fcc\u00fc ve hormonal denge desteklenir.<\/p>

              Topikal (Harici) Uygulamalar<\/strong><\/p>

              • Serum, losyon ve \u015fampuan formlar\u0131nda bulunur<\/li>
              • Do\u011frudan sa\u00e7 derisine uygulan\u0131r<\/li>
              • Genellikle kafein, peptitler veya bitkisel ekstraktlarla kombine edilir<\/li><\/ul>

                Topikal kullan\u0131m, \u00f6zellikle b\u00f6lgesel seyrelme ya\u015fayanlar veya sa\u00e7 ekimi sonras\u0131 sa\u00e7 derisi deste\u011fi i\u00e7in faydal\u0131d\u0131r.<\/p>

                Beklenen Sonu\u00e7lar ve Zaman \u00c7izelgesi<\/h2>

                Do\u011fal tedaviler zamanla etki g\u00f6sterir. Saw Palmetto sab\u0131r ve s\u00fcreklilik gerektirir.<\/p>

                S\u00fcre<\/strong><\/p><\/td>

                Kullan\u0131c\u0131lar\u0131n Genellikle Fark Ettikleri<\/strong><\/p><\/td>

                \u00d6nemli Notlar<\/strong><\/p><\/td><\/tr><\/thead>

                1\u20132 ay<\/p><\/td>

                Sa\u00e7 derisinde rahatlama, daha az hassasiyet<\/p><\/td>

                G\u00f6r\u00fcn\u00fcr sa\u00e7 \u00e7\u0131k\u0131\u015f\u0131 i\u00e7in erken<\/p><\/td><\/tr>

                3\u20136 ay<\/p><\/td>

                G\u00fcnl\u00fck d\u00f6k\u00fclmede azalma, k\u00f6klerde dolgunluk<\/p><\/td>

                D\u00fczenli kullan\u0131m \u015fart<\/p><\/td><\/tr>

                6\u201312 ay<\/p><\/td>

                Kal\u0131nl\u0131k ve yo\u011funlukta g\u00f6zle g\u00f6r\u00fcl\u00fcr art\u0131\u015f<\/p><\/td>

                Erken evrelerde daha etkili<\/p><\/td><\/tr>

                12+ ay<\/p><\/td>

                Sonu\u00e7lar\u0131n stabil hale gelmesi<\/p><\/td>

                Uzun vadeli bak\u0131m i\u00e7in uygun<\/p><\/td><\/tr><\/tbody><\/table>

                \u00d6nemli:<\/strong> Sonu\u00e7lar genetik, ya\u015f, hormonal durum ve genel sa\u011fl\u0131k durumuna g\u00f6re de\u011fi\u015fkenlik g\u00f6sterir.<\/p>

                Saw Palmetto\u2019yu Di\u011fer Do\u011fal \u0130\u00e7eriklerle Birlikte Kullanmak<\/h2>

                Sa\u00e7 d\u00f6k\u00fclmesi nadiren tek bir nedene ba\u011fl\u0131d\u0131r. Kombine form\u00fcller genellikle daha iyi sonu\u00e7 verir.<\/p>

                Yayg\u0131n sinerjik i\u00e7erikler:<\/strong><\/p>

                • Biotin (B7 vitamini):<\/strong> Keratin \u00fcretimini ve sa\u00e7 telinin dayan\u0131kl\u0131l\u0131\u011f\u0131n\u0131 destekler<\/li>
                • Kabak \u00e7ekirde\u011fi ya\u011f\u0131:<\/strong> Ek bir do\u011fal 5-alfa red\u00fcktaz engelleyici<\/li>
                • Kafein:<\/strong> Sa\u00e7 derisi dola\u015f\u0131m\u0131n\u0131 art\u0131r\u0131r ve DHT etkilerine kar\u015f\u0131 koyar<\/li>
                • Capixyl ve peptitler:<\/strong> Sa\u00e7 k\u00f6k\u00fcn\u00fc sabitlemeye ve b\u00fcy\u00fcme sinyallerini desteklemeye yard\u0131mc\u0131 olur<\/li><\/ul>

                  Klinik olarak dengelenmi\u015f form\u00fcller, rastgele \u00fcr\u00fcn kombinasyonlar\u0131na k\u0131yasla genellikle daha etkilidir.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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                  S\u0131k Sorulan Sorular<\/h2>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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                  Saw Palmetto ger\u00e7ekten DHT\u2019yi engeller mi? <\/div><\/span>\n\t\t\t\t\t\t\t\n\t\t\t<\/path><\/svg><\/span>\n\t\t\t<\/path><\/svg><\/span>\n\t\t<\/span>\n\n\t\t\t\t\t\t<\/summary>\n\t\t\t\t
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                  Evet. \u00c7al\u0131\u015fmalar, 5-alfa red\u00fcktaz\u0131 bask\u0131lad\u0131\u011f\u0131n\u0131 ve DHT aktivitesini azaltt\u0131\u011f\u0131n\u0131 g\u00f6stermektedir.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/details>\n\t\t\t\t\t\t

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                  Finasterid kadar etkili mi? <\/div><\/span>\n\t\t\t\t\t\t\t\n\t\t\t<\/path><\/svg><\/span>\n\t\t\t<\/path><\/svg><\/span>\n\t\t<\/span>\n\n\t\t\t\t\t\t<\/summary>\n\t\t\t\t
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                  Hay\u0131r, ancak daha hafiftir ve daha az yan etkiyle ili\u015fkilendirilir.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/details>\n\t\t\t\t\t\t

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                  Ne kadar s\u00fcrede sonu\u00e7 al\u0131n\u0131r? <\/div><\/span>\n\t\t\t\t\t\t\t\n\t\t\t<\/path><\/svg><\/span>\n\t\t\t<\/path><\/svg><\/span>\n\t\t<\/span>\n\n\t\t\t\t\t\t<\/summary>\n\t\t\t\t
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                  D\u00f6k\u00fclmede azalma genellikle 3\u20136 ay i\u00e7inde g\u00f6r\u00fcl\u00fcr; yo\u011funluk art\u0131\u015f\u0131 6\u201312 ay s\u00fcrebilir.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/details>\n\t\t\t\t\t\t

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                  Uzun s\u00fcreli kullan\u0131m g\u00fcvenli mi? <\/div><\/span>\n\t\t\t\t\t\t\t\n\t\t\t<\/path><\/svg><\/span>\n\t\t\t<\/path><\/svg><\/span>\n\t\t<\/span>\n\n\t\t\t\t\t\t<\/summary>\n\t\t\t\t
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                  \u00d6nerilen dozlarda genellikle g\u00fcvenlidir.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/details>\n\t\t\t\t\t\t

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                  Kad\u0131nlar kullanabilir mi? <\/div><\/span>\n\t\t\t\t\t\t\t\n\t\t\t<\/path><\/svg><\/span>\n\t\t\t<\/path><\/svg><\/span>\n\t\t<\/span>\n\n\t\t\t\t\t\t<\/summary>\n\t\t\t\t
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                  Evet. Androjen kaynakl\u0131 sa\u00e7 incelmesi ya\u015fayan kad\u0131nlar taraf\u0131ndan yayg\u0131n olarak kullan\u0131l\u0131r.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/details>\n\t\t\t\t\t\t

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                  Oral m\u0131 topikal mi daha iyi? <\/div><\/span>\n\t\t\t\t\t\t\t\n\t\t\t<\/path><\/svg><\/span>\n\t\t\t<\/path><\/svg><\/span>\n\t\t<\/span>\n\n\t\t\t\t\t\t<\/summary>\n\t\t\t\t
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                  Farkl\u0131 \u015fekillerde etki ederler. Uzman g\u00f6r\u00fc\u015f\u00fcyle kombine kullan\u0131m s\u0131kl\u0131kla \u00f6nerilir.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/details>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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                  Takviye kullanmaya veya tedavileri birle\u015ftirmeye ba\u015flamadan \u00f6nce mutlaka bir sa\u011fl\u0131k uzman\u0131na dan\u0131\u015f\u0131n. Bireysel sonu\u00e7lar; sa\u011fl\u0131k durumu, genetik yap\u0131 ve sa\u00e7 d\u00f6k\u00fclmesinin evresine ba\u011fl\u0131d\u0131r.<\/strong><\/p>

                  \"How-to-Use-Saw-Palmetto-Effectively\"<\/strong><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"

                  Sa\u00e7 d\u00f6k\u00fclmesi, d\u00fcnya genelinde en yayg\u0131n estetik sorunlardan biridir. Hem erkeklerde hem de kad\u0131nlarda, sorunun merkezinde \u00e7o\u011fu zaman tek bir hormon yer al\u0131r: DHT (dihidrotestosteron). Zamanla DHT, sa\u00e7 k\u00f6klerini zay\u0131flat\u0131r, […]<\/p>\n","protected":false},"author":1923,"featured_media":15463,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_joinchat":[],"footnotes":""},"categories":[104,73],"tags":[],"class_list":["post-14857","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-post-hair-transplant-treatment-tr","category-uncategorized-tr"],"acf":[],"_links":{"self":[{"href":"https:\/\/mdplusbio.com\/tr\/wp-json\/wp\/v2\/posts\/14857","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/mdplusbio.com\/tr\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/mdplusbio.com\/tr\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/mdplusbio.com\/tr\/wp-json\/wp\/v2\/users\/1923"}],"replies":[{"embeddable":true,"href":"https:\/\/mdplusbio.com\/tr\/wp-json\/wp\/v2\/comments?post=14857"}],"version-history":[{"count":0,"href":"https:\/\/mdplusbio.com\/tr\/wp-json\/wp\/v2\/posts\/14857\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/mdplusbio.com\/tr\/wp-json\/wp\/v2\/media\/15463"}],"wp:attachment":[{"href":"https:\/\/mdplusbio.com\/tr\/wp-json\/wp\/v2\/media?parent=14857"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/mdplusbio.com\/tr\/wp-json\/wp\/v2\/categories?post=14857"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/mdplusbio.com\/tr\/wp-json\/wp\/v2\/tags?post=14857"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}